f1-f12 keys do the same functions as 0-9 keys, they might as well free up the 0-9 keys for customary binds (and its a great movement for streamlining)
another method for streamlining the action menu could be those "como-rose"-style UI (in the fashion of Battlefield, L4d, Portal etc.), where you hold down action button, drag mouse to direction of action button, and release to perform action
Special actions will be available in certain conditions as usual (ie. if you are next to a door, the open door action will be available; or if you are next to a injured player, you can choose to pick him up or revive him etc.)
its more intuitive to pull off actions via mousedragging (como-rose style) than doing mousewheel+spacebar