You should make the city vibrant and varied, like one side is the suburbs for all the rich and well-off people, then there's a middle class neighborhood, filled with less expensive homes and virtually no parks. And then you have the ghettos, with run down apartments, lots of chain fences, poorly kept streets, maybe you can add the war-torn part of the city somewhere inside of here.
And then you have the financial district, where people from all walks of life come to work in a labyrinth of various businesses and enterprises, filled tall skyscrapers, dark alleyways (perfect for an insurgency *wink**wink*).
And of course the tourists' destination. Every major city has one. San Francisco has Fisherman's Wharf, Seattle has Belltown. This should have at least 1 famous landmark, a lot of shops and probably a pier over the city's ocean, if it has one.
And, of course, the University District. Drawing influences from Seattle's own UD, yours should have nightclubs, bars, a soccer stadium, a lot of bus stops, small apartments, and a lot of restaurants.
And, finally, you should have an industrial part of town, one where you can find hundreds of cargo containers, docks, and smoke stacks. Maybe you can somehow install the Chernarussian Electrical Grid somewhere in here.
Well, that's all I've got for now.
P.S. I'm not good at modding or texturing, but if you need help in any other way, I'd be glad to pony up my services.