I think I might have the same problem.
I installed my X-56 and was able to use it in Elite Dangerous and Arma 3. then I had to take a break for a few days due to my workload.
When I returned, it didn't work anymore. the software recognizes it when i want to programm it or calibrate it. But when I try to use the X-56 in the game (to start the engine or turn/tilt), it doesn't work.
I tried reinstalling the X-56 H.O.T.A.S software and drivers, but it didn't help.
Are there more trouble shooting ideas/solutions out there?
Thanks in advance