I have a similar problem:
"Operation Flashpoint: Updating version 1.00 to version 1.20...
Some error occurred during patch installation.
Patch file is probably dammaged. You may need to download it again.
Error in file CAMPAIGNS\1985.pbo, phase 1."
I've reinstalled the game about 13 times in the past few weeks to try and get it working. Oddly enough it worked before, but then started having random lockups, and I've not been able to make any updates since. I've also read the FAQs about this type of problem, and it's not helped (DMA is disabled, I've tried an updated BIOS, 4 in 1 drivers, etc). And I've downloaded the patch from different locations to try and ensure its integrity. I've even reinstalled windows to try and solve it.
My specs:
1GHz T-Bird
Abit KT7-RAID
512MB RAM
Asus V8200 Deluxe (Geforce3)
Any ideas?